At BIANCA CLINIC, Botox treatment begins with understanding your face as a whole—not just the wrinkles you wish to soften. We assess your facial anatomy, muscle movement, facial balance, and aesthetic goals to create a personalized injection plan designed for natural, harmonious results.
What Are Botox Injections?
Botox injections are an injectable treatment that uses botulinum toxin type A, a neurotoxin produced by the bacterium Clostridium botulinum. By suppressing nerve signals involved in muscle contraction, Botox helps reduce excessive muscle activity. In aesthetic medicine, it is used for various purposes, including treating expression lines such as forehead lines and frown lines between the eyebrows, a prominent jawline caused by enlarged masseter muscles, and excessive sweating in areas such as the underarms.
Whole-Face Assessment and Injection Design
No two faces age or move in exactly the same way. Rather than following a standardized injection pattern, our physicians assess each patient’s bone structure, muscle activity, previous treatments, and desired outcome, then adjust the injection sites and dosage accordingly. This allows us to create a Botox treatment plan that considers the balance of the entire face.
Designed for Natural Expression
One of the most common concerns about Botox is looking “frozen.” At BIANCA CLINIC, preserving natural facial movement is a key priority. Injection depth, placement, and dosage are carefully adjusted to soften expression lines while maintaining the natural expressions that make each patient look like themselves.
Treatment Plans for Different Facial Features
International patients come to us with a wide range of facial structures, muscle strength, ethnic backgrounds, and aesthetic goals. At BIANCA CLINIC, we take these differences—as well as previous treatment history—into account when creating an individualized treatment plan for each patient
Botulinum Toxin Products We Use
At BIANCA CLINIC, we offer carefully selected botulinum toxin products to support a personalized treatment approach. Rather than using the same product for every patient, your physician will recommend the most appropriate option based on the treatment area, your aesthetic goals, and your individual needs.
BOTOX Vista®
The only botulinum toxin product approved by Japan's Ministry of Health, Labour and Welfare (MHLW). Manufactured by Allergan, it has been used in aesthetic medicine for more than 25 years and is recognized for its consistent performance and well-established safety profile.
CORETOX®
A highly purified botulinum toxin developed by Medytox in South Korea. By removing complexing proteins associated with antibody formation, CORETOX® is designed to help reduce the risk of treatment resistance, making it a suitable option for patients who receive regular Botox treatments.
INNOTOX®
A ready-to-use liquid botulinum toxin developed by Medytox in South Korea. Because it does not require reconstitution before treatment, it supports consistent dosing and streamlined preparation. It is also formulated without human serum albumin or animal-derived ingredients.
How Many Units Do I Need?
The number of Botox units varies depending on the treatment area, muscle strength, facial anatomy, and your desired outcome. The guide below shows the estimated unit ranges for common treatment areas at BIANCA CLINIC. Your physician will determine the most appropriate dosage during your consultation.
How Long Do Botox Results Last?
Botox results typically begin to appear about 3 days after treatment, with the full effect usually developing around 2 weeks. The results generally last for approximately 3 months before gradually wearing off, and muscle activity typically returns to its original state within about 6 months.
However, the duration of results varies from person to person and depends on factors such as the treatment area, muscle strength, metabolism, and individual response to treatment. With repeated treatments, the targeted muscles may gradually become less active over time. As a result, many patients find that their results last longer and require less frequent maintenance.
At BIANCA CLINIC, we believe natural-looking results come from treating the face as a whole rather than focusing on a single concern. While Botox effectively softens dynamic wrinkles, combining Botox with treatments such as hyaluronic acid fillers and thread lifts when appropriate allows us to create balanced, harmonious facial results tailored to each individual.
Your skin, your choice.
The difference between continuing Botox and not.
Why Choose BIANCA CLINIC for Botox?
At BIANCA CLINIC, Botox treatment is built around individualized medical planning rather than standardized injection patterns. Every treatment is designed to achieve natural-looking results while respecting each patient's unique facial anatomy and aesthetic goals.
Physician-Led Treatment Design
Every Botox treatment begins with a detailed assessment by your physician. Facial anatomy, muscle movement, facial balance, and treatment goals are carefully evaluated to determine the most appropriate injection sites and dosage.
Personalized Product Selection
We offer multiple botulinum toxin products—including BOTOX Vista®, CORETOX®, and INNOTOX®—allowing your physician to select the most appropriate option based on the treatment area, muscle activity, treatment history, and your individual goals.
Comprehensive Facial Planning
Rather than treating wrinkles in isolation, we evaluate how Botox fits within your overall facial balance. When appropriate, we may recommend combining Botox with treatments such as hyaluronic acid fillers or thread lifts to create harmonious, natural-looking results.
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Treatment Process
Every treatment begins with understanding your goals and developing a personalized treatment plan. The following steps outline what you can expect throughout your Botox treatment at BIANCA CLINIC.
01
Doctor's Examination & Consultation
Your treatment begins with a comprehensive consultation and examination by one of our physicians. We will discuss your concerns and aesthetic goals while carefully assessing your facial anatomy, muscle movement, and treatment areas to determine the most appropriate injection plan. We will also explain the procedure, aftercare instructions, and any precautions before treatment. Please feel free to ask any questions during your consultation.
02
Makeup Removal & Preparation
If you arrive wearing makeup, you will be asked to remove it from the treatment areas so your physician can accurately assess your facial contours and skin condition. The treatment area will then be cleansed and disinfected before the procedure.
03
Treatment
Your physician will confirm the treatment areas before administering carefully planned injections using an ultra-fine needle. Depending on the treatment areas and dosage, the procedure typically takes 10–20 minutes.
04
Aftercare
After treatment, your physician will examine the treated areas and apply cooling if necessary. On the day of your procedure, please avoid rubbing or massaging the treated areas to ensure the best possible results.
Comprehensive Support for International Patients
We understand that many international patients visit Japan for a limited time. At BIANCA CLINIC, we strive to make your treatment experience as smooth and comfortable as possible by providing English-language consultations, personalized treatment planning, and clear aftercare guidance.
Our team will help you schedule your treatment appropriately and provide post-treatment instructions before you leave Japan, so you can return home with confidence. If you have any questions before or after your visit, our staff will be happy to assist you.
Price List
BOTOX INJECTIONS
PRODUCT
PRICE PER UNIT
BOTOX VISTA
¥900/ tax incl.
CORETOX
¥900/ tax incl.
INNOTOX
¥500/ tax incl.
Additional treatment fee: ¥25,500
ESTIMATED UNITS
Botox Lift: 40–60 units
Forehead: 6–10 units
Crow's Feet: 6–10 units
Almond Eyes: 2–4 units
Glabellar Lines: 6–10 units
Bunny Lines: 6–10 units
Nasal Bridge: 4 units
Nasal Ala: 4–6 units
Philtrum: 4–6 units
Mouth Corners: 4–6 units
Gummy Smile: 4 units
Masseter: 10–100 units
Chin: 10 units
Salivary Glands: 20–40 units
Neck: 40–100 units
Shoulders: 100–200 units
Calves: 100–400 units
Underarms: 40–120 units
Barbie Botox: 200 units
Head-tox (CORETOX Only): 100 units
Exo-tox (CORETOX Only): 100 units * Exosome: ¥100,000 per vial (charged separately).
Additional anesthesia and retouch within 2 weeks are included. Foreign currency estimates available on request. Pricing subject to change without notice.
A consultation, in your own time
Online first visits are available. Our concierge supports international guests from arrival to departure.
Most patients begin to notice results within about 3 days, with the full effect typically developing around 2 weeks after treatment. The exact timing varies depending on the treatment area, individual muscle activity, and the product used.
Q
How long do Botox results last?
A
Botox results generally last about 3 months before gradually wearing off. In many cases, muscle activity returns to its original state within approximately 6 months. With regular treatments, many patients find that the effects last longer over time.
Q
Will my face look frozen?
A
Not when treatment is properly planned. At BIANCA CLINIC, every treatment is customized according to your facial anatomy, muscle movement, and aesthetic goals to soften dynamic wrinkles while preserving natural facial expression.
Q
Is Botox painful?
A
Most patients experience only mild discomfort during treatment. Ultra-fine needles are used to minimize discomfort, and the procedure is typically completed within 10–20 minutes, depending on the treatment area.
Q
What should I avoid after Botox?
A
Avoid rubbing or massaging the treated area on the day of your procedure. Your physician will also provide personalized aftercare instructions based on your treatment plan to help achieve the best possible results.
Q
How many Botox units will I need?
A
The number of units needed varies depending on the treatment area. As a general guide, approximately 6–10 units may be used for the forehead, 6–10 units for the frown lines, 6–10 units for the crow’s feet, and 10–100 units for the jawline.
However, the appropriate dosage varies depending on factors such as muscle strength, facial structure, and your desired outcome. At BIANCA CLINIC, your physician will determine the appropriate number of units for you based on an individual assessment and consultation.
Q
Can international patients receive Botox during a short stay in Japan?
A
Yes. Many international patients visit BIANCA CLINIC while traveling in Japan. We provide English-language consultations, personalized treatment planning, and aftercare guidance to help make your treatment experience smooth and comfortable.
Q
Can Botox be combined with other treatments?
A
Yes. Botox can be combined with treatments such as hyaluronic acid fillers and thread lifts when appropriate. Your physician will recommend a personalized treatment plan based on your facial anatomy, concerns, and aesthetic goals.
Case Details
Treatment
Botox Injections
Recommended Treatment Interval
Approximately one treatment every 3–6 months, depending on your individual condition and treatment goals.
Potential Risks & Side Effects
Swelling, bruising, temporary facial stiffness, infection, and other potential complications.
Important Information Regarding Unapproved Medical Products
BOTOX VISTA® has been approved by Japan's Ministry of Health, Labour and Welfare (MHLW) for the treatment of glabellar lines (frown lines) and crow's feet in adults under 65 years of age (Approval No. 22100AMX00398000).
However, depending on the physician's clinical judgment, the product may be used for treatment purposes or injection sites that differ from the approved indications.
Some of the products used in this treatment are imported into Japan through a physician-directed personal importation process. For more information, please refer to the Ministry of Health, Labour and Welfare's guidance regarding the personal importation of pharmaceuticals:
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
In some cases, there may be no approved equivalent pharmaceutical products in Japan with the same active ingredient or performance.
Safety information in other countries
CORETOX® has been approved by the Korean Ministry of Food and Drug Safety (MFDS).
INNOTOX® has been approved by the Korean Ministry of Food and Drug Safety (MFDS).
Please note that if a serious adverse event occurs following treatment with an unapproved product, you may not be eligible for compensation under Japan's government relief system for adverse drug reactions.
