RADIESSE
An Injectable Treatment for a Range of Concerns
- Point 1 : 01 RADIESSE hyperdilute treatment supports skin firmness and elasticity
- Point 2 : 02 RADIESSE calcium hydroxylapatite (CaHA) helps guide the skin toward a healthy, firm appearance
- Point 3 : 03 From skin quality to facial contouring — injection design tailored to your goals and RADIESSE treatment areas
Interpretation and counseling services are free of charge.
*Some doctors may require an additional fee for selection.
The Author
DR. AIRI YOKOYAMA
JUVEDERM VISTA CERTIFIED / BOTOX VISTA CERTIFIED
Dr. Airi studied at Hiroshima University, Faculty of Medicine, and began her career in general medicine before transitioning to aesthetic medicine to enrich patients' lives through beauty.She has significant leadership experience, having helped establish a clinic where she served as director for three years, examining approximately 20,000 patients. While her primary focus is on cosmetic dermatology and achieving natural beauty, she also performs surgical procedures for the eye area.With experience from three overseas study programs and fluency in both Japanese and English, she is dedicated to providing safe, high-quality treatments to international patients. Her specialties include anti-aging care, injections, treatments for sagging skin, and skin rejuvenating boosters.
Our Approach at BIANCA CLINIC
Undiluted RADIESSE works differently — for contouring or volume correction, the injection layer is chosen based on your anatomy and goals.
RADIESSE started out as a filler for volume correction and contouring, injected undiluted — and that's still the traditional standard.
More recently, though, a diluted, hyperdilute version has also gained traction internationally.
At BIANCA CLINIC, the dilution ratio is set for your treatment area and skin condition — the RADIESSE procedure is never one-size-fits-all. From there, careful injection design and precise technique take over. RADIESSE is thought to support your skin's own collagen and elastin production — the aim, always, is a natural-looking result, tailored to you.
A consultation, in your own time
Online first visits are available. Our concierge supports international guests from arrival to departure.
Downtime
RADIESSE downtime is typically minimal, and RADIESSE recovery time varies by individual:
・Shower: Available from the day of treatment
・Bruising: Resolves naturally within about 1–2 weeks
・Makeup: Available from the day of treatment
・Discomfort: A brief pricking sensation during injection
・Treatment time: About 30 minutes
・Redness: Resolves naturally within about 3 days to 1 week
Recommended for
- Skin that feels thin or lacking in firmness
- Hollow-looking or sagging cheeks after weight loss
- Horizontal lines on the neck or décolletage
- A more youthful look for aging hands
- Building a stronger skin foundation as part of preventative skin care
- A sharper jawline or nose bridge, closer to an ideal E-line
Characteristics
As a RADIESSE dermal filler, it supports volume correction and contouring, filling in wrinkles and hollows. But RADIESSE as a biostimulator does more than that — it's also thought to work as a RADIESSE collagen stimulator, supporting your skin's own production of collagen and elastin.
The mechanism: CaHA is believed to stimulate fibroblasts, which in turn support the production of collagen, elastin, and other components of the extracellular matrix (ECM)*. Over time, that can translate into visible RADIESSE results — changes in skin quality that build gradually.
How much, and for how long, depends on the treatment area, injection method, and amount used. Results vary by individual.
*Biostimulator: a general term for treatments or formulas that support the skin's own production of collagen and other components to help improve firmness and elasticity.
*ECM (extracellular matrix): made up of collagen, elastin, and other components that support the structure of tissue surrounding cells.
It's not just for the face, either. RADIESSE neck treatment, along with the décolletage and backs of the hands — the areas that tend to show age first — follows the same approach.
Because it supports your skin's own collagen and elastin production, the treatment aims to achieve a naturally youthful appearance.
A few examples:
・Correction of deep lines such as nasolabial folds and marionette lines
・RADIESSE jawline contouring for a more defined E-line
Its elasticity makes it well suited for contouring, and it's thought to support collagen and elastin production along the way — contributing to firmer, more resilient skin.
So beyond the volume correction you see right away, RADIESSE's CaHA content is also expected to keep stimulating collagen production over time.
Benefit
Supports Goals from Skin Quality to Contouring
Addresses the Skin's Foundation (ECM)
Injection Design Tailored to the Treatment Area
Key features
Hyperdilute treatment targets the more superficial layers of the skin. Undiluted injection goes deeper. Our physicians, who have a thorough command of anatomy, determine the right layer for the purpose and treat with care.
Changes in skin thickness and texture can be expected over time, building toward a healthy, youthful appearance. For that reason, RADIESSE fits naturally into a long-term approach to aging care.
Each area gets its own treatment plan, built around its specific concerns. Wondering whether RADIESSE could work for a particular spot? Your physician will walk through it with you at your consultation.
A consultation, in your own time
Online first visits are available. Our concierge supports international guests from arrival to departure.
Treatment Area
Forehead · Temples · Cheeks · Nasolabial folds · Marionette lines
Chin · Jawline · Neck · Décolletage · Backs of the hands
Treatment Process
Physician Consultation
Every detail of the treatment gets explained. Please feel free to ask any questions.
Makeup Removal
Treatment
Price List
| TREATMENT | PRICE |
|---|---|
| RADIESSE | ¥115,500/ tax incl. |
Additional anesthesia and retouch within 2 weeks are included. Foreign currency estimates available on request. Pricing subject to change without notice.
A consultation, in your own time
Online first visits are available. Our concierge supports international guests from arrival to departure.
Concept
Going beyond the realm of
cosmetic medicine,
we propose Lifestyle Beauty.
Our goal is to provide an experience that goes beyond mere satisfaction, a truly moving one.
Responding to the desire to “become more beautiful and healthy,”
what can we do for our patients’ happiness?
Providing total beauty that makes life shine—
That is our clinic’s policy.
BIANCA is a place where you can leave with a smile.
That’s the kind of place we aim to be.
FAQ
Is there discomfort or downtime with this treatment?
To help minimize discomfort, your physician uses either a needle or a blunt-tipped microcannula, chosen for the injection site and treatment goal.
If you’re concerned about discomfort, anesthesia is available — just ask.
Downtime may involve mild swelling and redness, and occasionally slight bruising, but these are generally mild enough to cover with makeup.
What is the hyperdilute method?
RADIESSE is diluted — typically with saline — before injection.
Rather than adding volume, the main goal is supporting skin quality through CaHA’s effect on collagen and elastin production. Diluted and hyperdilute CaHA treatments have also been reported internationally for use on the face, neck, and décolletage.
Is the hyperdilute method also used for the jawline or nose?
Generally, no. For contouring the jawline or nose, or filling in wrinkles and hollows like nasolabial folds and cheek volume loss, undiluted RADIESSE is the standard choice.
The hyperdilute method is reserved for skin-quality goals.
Is RADIESSE under eyes or RADIESSE lip filler treatment available at BIANCA CLINIC?
No. Because the skin under the eyes and on the lips is thin and delicate, injecting RADIESSE there carries a higher risk of nodules or irregularities — so BIANCA CLINIC doesn’t perform RADIESSE treatment in these areas.
What's the difference between RADIESSE and hyaluronic acid filler?
Hyaluronic acid filler has a soft texture and is used mainly for volume correction and contouring.
RADIESSE, by contrast, has a thicker, slightly firmer texture — and beyond volume correction and contouring, it’s known for supporting firmer skin from within.
Can RADIESSE be used on the body as well as the face?
Yes. At BIANCA CLINIC, RADIESSE is also used on the neck, décolletage, and backs of the hands.
Ask your physician for details at your consultation.
Are there RADIESSE risks like RADIESSE lumps or RADIESSE nodules after treatment?
Reducing the risk of RADIESSE nodules comes down to injecting into the right layer, in the right amount.
At BIANCA CLINIC, injection site, layer, and volume are all carefully determined based on anatomy, with this risk in mind throughout treatment.
Can the treated area turn into bone?
CaHA, RADIESSE’s main component, is also found naturally in bone — but the treatment isn’t designed to turn the injected material into bone.
At BIANCA CLINIC, physicians with a thorough command of anatomy perform every treatment with close attention and care.
Will it show up on X-rays or CT scans?
Yes. CaHA, RADIESSE’s main component, can appear as a white area on X-rays or CT scans. If you’re having one of these scans, let your doctor or dentist know beforehand that you’ve had RADIESSE treatment.
Treatment Details & Important Safety Information
Periodic repeat injections may be recommended to maintain treatment-related changes.
In rare cases, serious complications such as vascular occlusion and associated skin damage or necrosis, or visual impairment, may occur.
The pharmaceutical used in this treatment is individually imported under the physician's judgment. For details, please refer to the Ministry of Health, Labour and Welfare's information on individually imported pharmaceuticals requiring caution:
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There is no approved pharmaceutical in Japan with the same ingredients or performance as RADIESSE®.
・Correction of moderate to severe facial wrinkles and folds (such as nasolabial folds)
・Improvement of volume loss on the backs of the hands (hand augmentation)
・Correction of décolletage wrinkles in patients aged 22 and older (using a 1:2 saline dilution protocol)
Serious risks or side effects may exist that have not yet been identified.
In the rare event of a serious side effect, it may not be covered under Japan's Relief System for Sufferers from Adverse Drug Reactions.
A consultation, in your own time
Online first visits are available. Our concierge supports international guests from arrival to departure.