RETATRUTIDE
A weight management approach targeting three hormone receptors
- Punto 1: 01 A new approach targeting three receptors: GIP, GLP-1, and glucagon
- Punto 2: 02 Focuses not only on appetite control and blood sugar regulation, but also on energy metabolism
- Punto 3 : 03 Designed as a once-weekly subcutaneous injection
Los servicios de interpretación y asesoramiento son gratuitos.
*Algunos médicos pueden exigir una tarifa adicional para la selección.
El autor
DR. YOKO MAEDA
Board-Certified Specialist, American Academy of Anti-Aging Medicine (A4M) / Director, Japan Society of Aesthetic Internal Medicine
Graduada de la Facultad de Medicina de la Universidad de Hiroshima, la Dra. Maeda es una especialista certificada en EE. UU. y Japón en medicina estética y regenerativa, que ofrece tratamientos avanzados como la terapia hormonal y la terapia con péptidos. Es conocida por su enfoque amable y basado en la ciencia hacia la belleza natural y continúa estudiando las últimas innovaciones médicas con pasión por el aprendizaje continuo.
Nuestro Enfoque en BIANCA CLINIC
Interest in retatrutide has grown as researchers explore its role in weight management and the multiple pathways involved in body weight regulation. Our physicians carefully review available international clinical data and current medical evidence before considering treatment for each client. We take the time to review your lifestyle, medical history, diet, and other relevant factors, considering not only your current health but also your long-term well-being.
We also provide a thorough explanation of the potential risks and limitations of treatment before you decide whether to proceed. Our priority is to ensure that you understand the treatment and feel comfortable with your decision while we support your journey toward health and beauty from within.
Una consulta, cuando tengas tiempo
Las primeras visitas en línea están disponibles. Nuestro conserje ayuda a los huéspedes internacionales desde su llegada hasta su partida.
Tiempo de inactividad
Bruising: Usually fades naturally within a few days
Makeup: Can be applied on the same day
Discomfort: A brief, mild pinprick may be felt during the injection
Treatment Time: A few minutes
Showering / Bathing: Allowed on the same day
During the initial stage of treatment, gastrointestinal side effects such as nausea, vomiting, diarrhea, constipation, and decreased appetite may occur. These symptoms often ease over time. If they are severe or persist, contact your physician.
Recomendado para
- Those looking to reduce their daily food intake
- Those who want support with weight management beyond exercise alone
- Those looking to maintain their weight and reduce the likelihood of weight regain
- Those interested in trying a different approach to weight management
- Those who have noticed changes in their metabolism and want to take a broader approach to weight management
- Those looking for a structured treatment plan with fewer clinic visits
- Those looking to achieve healthy weight loss with support from a physician
Características
Mounjaro (tirzepatide), which is also available at BIANCA CLINIC, is one example of the latter.
In contrast, retatrutide is a triple agonist that acts on three receptors—GLP-1, GIP, and glucagon. With this distinct mechanism of action, retatrutide is attracting attention as a new approach to medical weight management.
Together, these pathways allow retatrutide to target appetite, blood sugar control, and energy metabolism as part of a multi-pathway approach to weight management.
Treatment begins with a low dose, which is gradually adjusted under physician supervision based on your condition and response to treatment. At BIANCA CLINIC, we look beyond changes in body weight alone. We also monitor changes in your overall condition and daily lifestyle, supporting treatment at a pace tailored to your individual needs.
Beneficios
Targets Both Appetite and Energy Metabolism
Dosing Adjusted to Your Individual Needs
Can Be Combined with Lifestyle Changes
Características principales
At your initial consultation, blood tests will also be performed to assess your health before treatment. Once treatment begins, we will regularly monitor changes in your overall condition and body weight.If you have any concerns or questions during treatment, please feel free to discuss them with your physician.
At BIANCA CLINIC, retatrutide treatment is combined with nutritional therapy and personalized lifestyle guidance. We also offer comprehensive wellness approaches tailored to each client's lifestyle and individual background, including epigenetic clock testing to assess biological age and orthomolecular nutritional therapy.
Rather than focusing only on short-term changes in weight, we support you in reviewing your daily habits with the goal of reducing the risk of weight regain and promoting long-term health and weight management.
Una consulta, cuando tengas tiempo
Las primeras visitas en línea están disponibles. Nuestro conserje ayuda a los huéspedes internacionales desde su llegada hasta su partida.
Área de tratamiento
Proceso de tratamiento
Consultation and Physician Assessment
Your physician will then assess your overall health, explain the characteristics of retatrutide, and determine whether the treatment is appropriate for you.
Análisis de sangre (sólo primera visita)
Tratamiento
At your first treatment, our medical staff will carefully explain how to use the pen, how to administer the injection, and the precautions to follow.
We will also provide guidance on nutrition and lifestyle habits to support you throughout your treatment.
Lista de precios
RETATRUTIDE
| Dosis / Notas | PRECIO | Notas |
|---|---|---|
| 4mg (Month 1) | ¥73,500/ impuestos incluidos. | Equivalent to 2.5 mg of Mounjaro |
| 8mg (Month 2) | 115.500 ¥/ impuestos incluidos. | Equivalent to 5 mg of Mounjaro |
| 16mg (Month 3) | ¥189,000/ impuestos incluidos. | Equivalent to 7-10 mg of Mounjaro |
・Consultation fee: ¥12,100 / tax incl.(for the initial prescription only).
・Blood test fee: ¥3,300/ tax incl. (for the initial visit only).
・Disinfection and needle fees are included.
・Blood tests are available Monday through Saturday only (not available on Sundays or public holidays).
La anestesia adicional y el retoque en un plazo de 2 semanas están incluidos. Presupuestos en moneda extranjera disponibles previa solicitud. Precios sujetos a cambios sin previo aviso.
Concepto
Más allá del ámbito de
medicina estética,
proponemos Lifestyle Beauty.
Nuestro objetivo es ofrecer una experiencia que va más allá de la mera satisfacción, una verdaderamente conmovedora.
Respondiendo al deseo de “volverse más bella y saludable,”
¿Qué podemos hacer por la felicidad de nuestros pacientes?
Proporcionando una belleza total que hace brillar la vida—
Esa es la política de nuestra clínica.
BIANCA es un lugar del que puedes salir con una sonrisa.
Ese es el tipo de lugar que aspiramos a ser.
PREGUNTAS FRECUENTES
What is the difference between retatrutide and Mounjaro (tirzepatide)?
Mounjaro (tirzepatide) acts on two receptors, GIP and GLP-1, while retatrutide acts on three receptors: GIP, GLP-1, and glucagon. The difference in receptor targets does not make one treatment the better choice for everyone. Which option may be considered depends on the individual.
At BIANCA CLINIC, we carefully review your previous treatments, any symptoms you have experienced, and your current health before recommending an appropriate treatment approach for your individual needs.
How long does it take to notice changes with retatrutide?
There is no single timeline that applies to everyone. Clinical trials have reported changes over several weeks to several months of continued treatment.
At BIANCA CLINIC, we generally recommend continuing treatment for at least three to six months, even when considering a relatively short treatment period.
Your physician will monitor your progress and adjust the treatment plan based on your health, response, and lifestyle.
What are the side effects of retatrutide?
The most commonly reported side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, as well as decreased appetite and fatigue.
These symptoms are more likely to occur during the initial stage of treatment and may gradually improve over time.
If your symptoms are severe or persist, please contact your physician promptly rather than waiting for them to resolve on their own.
Is there any downtime after a retatrutide injection?
Because retatrutide is administered by injection rather than surgery, there is generally no downtime comparable to that associated with a surgical procedure. However, redness or swelling may occur at the injection site.
These symptoms often subside over time. If you experience persistent or concerning symptoms, please discuss them with your physician.
Can anyone receive retatrutide treatment?
No. Retatrutide treatment is not suitable for everyone. It cannot be provided during pregnancy or while breastfeeding. Depending on factors such as your BMI, medical history, and current medications, you may also be ineligible for treatment.
At BIANCA CLINIC, a physician will carefully assess your individual condition through a medical examination and blood tests before determining whether retatrutide treatment is appropriate for you.
Will I regain weight after stopping retatrutide?
Weight regain is possible after stopping treatment, particularly if previous lifestyle habits return.
This is why diet, exercise, and other lifestyle habits are worth addressing while treatment is still underway.
What should I keep in mind while receiving retatrutide treatment?
In addition to medication-based weight management, maintaining a balanced diet, getting appropriate exercise, and reviewing your overall lifestyle habits are important.
Throughout treatment, your physician will monitor changes in your condition and provide guidance as needed.
TREATMENT DETAILS
The treatment schedule may vary depending on your individual condition.
・The medication used for this treatment is imported through individual import procedures under the supervision and judgment of a physician. For more information, please refer to the Japanese Ministry of Health, Labour and Welfare’s guidance on medications requiring caution when imported for personal use:https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
・There are currently no medications approved in Japan that contain the same active ingredient.
・As of September 2026, retatrutide has not been approved in the United States or other major Western countries, and clinical trials evaluating its safety and efficacy are ongoing. Therefore, some serious risks may not yet have been fully identified.
・In the event of a serious adverse reaction, you may not be eligible for compensation under Japan’s Adverse Drug Reaction Relief System.
Una consulta, cuando tengas tiempo
Las primeras visitas en línea están disponibles. Nuestro conserje ayuda a los huéspedes internacionales desde su llegada hasta su partida.