We have newly introduced Re2o, a next-generation skin booster that directly supplements lost collagen and supports healthier skin quality from within. By addressing the skin’s foundation, it aims to help guide the skin toward a smoother and more resilient state.
Re2o Key Points
- Works directly on the “foundation of the skin” rather than the surface, guiding skin toward a more youthful appearance
- A human-derived collagen formulation designed with an emphasis on skin compatibility
- An injection-based treatment designed with ease of continuation and reduced treatment burden in mindH2: Re2o at BIANCA CLINIC
Re2o at BIANCA CLINIC － Expertise in Injection Techniques Makes the Difference
Re2o (Bonajour) is administered manually by a physician who carefully evaluates each patient’s skin condition. Because injection depth, volume, and placement directly affect results, outcomes largely depen on the injector’s expertise.
At our clinic, treatments are performed by physicians with extensive experience in aesthetic injections. Upon request, we can also conduct an objective skin analysis using VISIA® imaging during consultation. By assessing your skin condition before and after treatment, we create a fully customized treatment plan designed for optimal results.
Downtime
After the treatment, temporary swelling, puffiness, or redness may occur at the injection site.
Who Re2o Is Recommended For
- Those concerned about dark circles or hollowness under the eyes
- Individuals seeking improvement in forehead or glabellar lines
- Those noticing neck wrinkles
- Individuals experiencing reduced skin firmness
- Those concerned about nasolabial folds
- Patients wishing to improve overall skin quality
- Those concerned about enlarged pores
Re2o Characteristics
What Is Re2o?
Re2o is a next-generation collagen formulation whose main component is human Acellular Dermal Matrix (hADM), carefully extracted and purified from human tissue. It directly addresses concerns such as under-eye dark circles and age-related wrinkles, helping restore natural, youthful beauty from within.
A key feature of Re2o’s ingredients is their balanced inclusion of Type I collagen, which structurally supports the dermis, and Type III collagen, essential for maintaining smooth, youthful skin architecture. By incorporating both types, Re2o efficiently replenishes collagen lost through aging while supporting the skin’s natural healing processes and structural stability.
A Skin Booster That Directly Replenishes ECM Components
Skin firmness and elasticity are fundamentally supported by the extracellular matrix (ECM) — a network-like structural foundation surrounding skin cells. The ECM not only maintains tissue integrity but also facilitates cellular communication that preserves youthful skin.
With age, ECM components diminish and change, contributing to wrinkles and sagging. The re2o effect works by directly supplementing these foundational ECM components within the skin.
By restoring the structural base, it promotes firmness, elasticity, and hydration in a natural and sustained manner — not through temporary stimulation, but by supporting the skin’s architecture itself.
How Re2o Differs from Conventional Skin Boosters
Many traditional skin boosters stimulate the skin to “produce” collagen through controlled irritation. While effective in activating the body’s natural healing response, results may vary when cellular responsiveness has declined due to aging. What sets Re2o apart — as reflected in Re2o skin booster reviews — is its approach of directly supplementing human-derived ECM components such as collagen and elastin, rather than relying solely on the body’s own production capacity. This allows structural improvement without depending on cellular responsiveness, offering potential benefits even for patients who previously experienced limited results with other treatments.
Re2o Benefits
Addresses Multiple Skin Concerns from the Foundation
By replenishing core ECM components, re2o treatment helps improve not only wrinkles but also firmness, texture, and hydration — approaching skin concerns comprehensively from the structural level.
Highly Biocompatible Human-Derived Collagen
Because the formulation of re2o ingredients is derived from human collagen, it is considered highly biocompatible. This minimizes the likelihood of foreign body reactions while supporting a natural-looking finish.
Short Treatment Time with Consideration for Skin Comfort
The Re2o injection procedure involves injection only and requires minimal treatment time. As downtime is generally limited, it is suitable for patients with busy schedules.
Re2o Treatment Considerations
Difference Between Hyaluronic Acid Injections and Re2o
Both hyaluronic acid injections and re2o injection / re2o treatment involve injecting a formulation directly into the skin, but their purposes differ.
Hyaluronic acid injections primarily restore volume to specific areas or physically fill deeper wrinkles and depressions. The injected product gradually integrates and is absorbed over time.
In contrast, Re2o aims to improve the skin’s structural foundation. The injected collagen does more than simply fill space; it interacts with the skin’s internal environment and may function as a scaffold that supports cellular activity. Rather than focusing solely on volume replacement, Re2o seeks structural reconstruction from within and is often evaluated through re2o before after observations.
Natural Integration and Finish
Because Re2o replenishes ECM structural components naturally present in the skin, it integrates smoothly into the tissue.
The soft formulation minimizes the risk of unevenness or translucency, even in delicate areas such as the under-eye region. This allows subtle refinement of fine lines that may be difficult to treat with hyaluronic acid or botulinum toxin alone, contributing to an overall improvement in skin quality.
Microcannula Technique to Reduce Pain and Bruising
To enhance patient comfort, we utilize a microcannula technique during Re2o treatment. Unlike conventional sharp needles, microcannulas are thin and have a rounded tip, which helps reduce trauma to blood vessels and surrounding tissue. This approach may lower the risk of post-procedural bruising and swelling, making treatment in delicate areas such as the under-eye region more reassuring. As with any injectable procedure, mild Re2o side effects such as temporary redness or swelling may occur, though these typically resolve within a few days.
Re2o Treatment Areas
- Fine wrinkles around the eyes
- Forehead lines
- Glabellar lines (between the eyebrows)
- Nasolabial folds
Re2o Treatment Process
Medical Examination & Consultation
During the consultation, we carefully review your concerns and treatment goals. After assessing your skin condition, the physician will determine whether Re2o is appropriate for you.
We then provide a detailed explanation of the procedure, treatment flow, and associated costs before proceeding.
Makeup Removal (Treatment Area)
Before the procedure, makeup removal and facial cleansing are required for the treatment area.
Cleansing products and facial wash are available at our clinic.
Procedure
Re2o is injected into the designated treatment areas using a microcannula by a physician.
Procedure time varies depending on the area and extent of injection, but approximately 10 minutes is typical. After confirming hemostasis at the injection site, the treatment is completed.
Aftercare
The physician will review the results with you. If there are no concerns, you may apply makeup and return home the same day.
Temporary redness may occur at the injection site but typically subsides gradually over time.
Re2o – Frequently Asked Questions
How long do the effects of Re2o last?
Effects of re2o skin booster generally last 6 months to 1 year, although results vary by individual.
What is the ideal treatment frequency?
Initial treatment is often recommended in multiple sessions. Following this, a personalized maintenance plan is proposed based on your skin condition and the results of your Re2o treatment.
What should I know before undergoing treatment?
Re2o uses human-derived components, and patients who receive treatment may not be eligible to donate blood afterward.
What treatments pair well with Re2o?
Combination therapies may be considered depending on goals and skin condition during consultation.
Is Re2o safe?
Re2o is generally well tolerated because it uses human-derived components, though re2o side effects such as temporary swelling or redness may occur.
When can I apply makeup after treatment?
Makeup can usually be applied on the same day, provided the injection sites are avoided.
When can I shower or bathe?
Showering is permitted on the same day. Bathing is recommended from the day after treatment onward.