In the evolving field of aesthetic medicine, patients increasingly seek treatments that provide natural-looking results, long-term safety, and minimal downtime.
One product line that has gained global recognition for meeting these expectations is NEAUVIA, an innovative hyaluronic acid filler system developed using advanced biotechnology.
Unlike conventional fillers, NEAUVIA combines high-purity hyaluronic acid with unique cross-linking technology, creating a product designed to mimic the body’s own tissue structure while maintaining excellent durability and biocompatibility.
NEAUVIA is a medical-grade hyaluronic acid dermal filler used to restore volume, improve skin quality, and enhance facial contours.
Hyaluronic acid (HA) is a naturally occurring molecule in the skin responsible for hydration, elasticity, and structural support. As we age, HA levels gradually decline, leading to:
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Volume loss
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Fine lines and wrinkles
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Reduced skin elasticity
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Facial sagging
NEAUVIA fillers help replenish this lost hyaluronic acid, restoring youthful facial balance while maintaining a soft, natural appearance.
Advanced Technology: PEG Cross-Linking
One of NEAUVIA’s defining features is its use of PEG cross-linking technology.
Traditional hyaluronic acid fillers often rely on chemical cross-linking agents that may increase the risk of inflammation in sensitive patients. NEAUVIA instead uses polyethylene glycol (PEG), which offers several advantages:
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High biocompatibility
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Reduced risk of inflammatory reactions
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Longer-lasting structural stability
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Smooth and natural integration with surrounding tissues
This technology helps create fillers that feel soft yet supportive, making them suitable for both delicate areas and structural contouring.
Key Treatment Areas
NEAUVIA fillers are versatile and can be used in multiple facial areas, including:
1. Cheeks and Midface
Restore volume loss and lift the midface for a refreshed appearance.
2. Nasolabial Folds
Soften deep smile lines between the nose and mouth.
3. Lips
Enhance lip shape, hydration, and definition while maintaining natural movement.
4. Tear Troughs (Under-Eye Area)
Improve the appearance of dark circles and hollowness.
5. Jawline and Chin
Enhance facial structure and definition for a more balanced profile.
Because of its unique rheological properties, NEAUVIA allows physicians to customize treatments according to each patient’s anatomy and aesthetic goals.
Benefits of NEAUVIA Fillers
Patients and physicians choose NEAUVIA for several reasons:
Natural-looking results
The filler integrates smoothly into tissues, avoiding an overfilled or artificial look.
High purity formulation
Manufactured using pharmaceutical-grade hyaluronic acid.
Versatility
Different formulations are designed for superficial skin rejuvenation, deep structural support, and body treatments.
Long-lasting effects
Results typically last 9–18 months, depending on the treatment area and individual metabolism.
Minimal downtime
Most patients can return to daily activities immediately after treatment.
Safety and Considerations
As with any injectable treatment, NEAUVIA procedures should always be performed by a qualified medical professional.
Possible temporary side effects include:
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Mild swelling
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Redness at the injection site
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Bruising
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Tenderness
These symptoms typically resolve within a few days.
A thorough consultation with a physician ensures that the treatment plan is safe, personalized, and aligned with the patient’s expectations.
Different Neauvia for different needs
NEAUVIA Intense
Purpose: Structural support and deep volume restoration
Key characteristics
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High elasticity (high G’)
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Strong lifting capacity
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Designed for deep dermis or supraperiosteal injection
Common treatment areas
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Cheeks and midface
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Nasolabial folds
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Chin and jawline contouring
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Facial volume loss
NEAUVIA Intense Lips
Purpose: Lip enhancement and contour definition
Key characteristics
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Moderate elasticity
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Softer gel designed for dynamic areas
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Smooth integration with lip tissue
Common treatment goals
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Lip volume enhancement
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Lip border definition
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Correction of asymmetry
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Hydration and softness
NEAUVIA Stimulate
Purpose: Volume restoration combined with collagen stimulation
Key characteristics
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Hybrid formula containing calcium hydroxyapatite (CaHA)
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Biostimulatory effect for collagen production
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Medium to high lifting capacity
Common treatment areas
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Cheeks
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Jawline
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Lower face contouring
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Skin quality improvement
NEAUVIA Hydro Deluxe
Purpose: Skin hydration and quality improvement
Key characteristics
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Low cross-link density
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High HA concentration
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Designed for superficial dermal injections
Common treatment areas
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Face
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Neck
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Décolletage
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Hands
Benefits
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Improves skin hydration
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Enhances skin elasticity
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Provides subtle glow and texture improvement
Summary: Differences Between NEAUVIA Fillers
| Product | Main Function | Injection Depth | Best For |
|---|---|---|---|
| Intense | Deep structural volume | Deep dermis / supraperiosteal | Cheeks, jawline, chin |
| Intense Lips | Lip contour and volume | Dermis / mucosal layer | Lips |
| Stimulate | Volume + collagen stimulation | Deep dermis | Skin laxity, contouring |
| Hydro Deluxe | Skin hydration booster | Superficial dermis | Skin quality improvement |
BIANCA’S doctor Dr. Yukitaro, first KOL in Japan for NEAUVIA
Japan’s first-ever KOL training using NEAUVIA fillers was conducted by world-renowned Global KOL Dr. Luciano Lanfranchi and Japan’s KOL Dr. Yukitaro Ikeda of BIANCA CLINIC.

Before After

Upper: before, Below: after
Cost: NEAUVIA intense 165,000¥ / 1ml, Juvederm 87,400¥ / 1ml, injection fee 24,200¥, microcannula 2,420¥ /1
Risks: bruises, internal bleeding, swelling, allergy…
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Walk-ins are welcome!
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Clinic Locations
📍 Ginza Clinic
12F Ginza ONE, 1-8-19 Ginza, Chuo-ku, Tokyo, Japan
☎ 050-3196-4834
📍 Omotesando Clinic
Minami-Aoyama 511 Building 2F, 5-11-10 Minami-Aoyama, Minato-ku, Tokyo, Japan
☎ 050-1807-1593
Consultation Hours: 10:00–19:00 Closed: Irregular holidays
About BIANCA Clinic
At BIANCA, we redefine beauty care by offering a holistic approach that transcends traditional cosmetic surgery and dermatology. 20 specialized doctors in different fields including plastic surgery, dermatology, internal medicine, regenerative medicine, gynecology will carefully listen to your needs and help you to enhance your beauty and wellness from the inside out. We are committed to creating personalized treatment plans with precision and care, and ensuring you experience the true spirit of Japanese omotenashi and hospitality.