Bioidentical Hormone Replacement Therapy
Interpretation and counseling services are free of charge.
*Some doctors may require an additional fee for selection.
Treatment Area
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Oral capsules: Progesterone, DHEA, Thyroid hormone, Melatonin
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Topical creams: Estrogen, Testosterone
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Injections: Male testosterone
Interpretation and counseling services are free of charge.
*Some doctors may require an additional fee for selection.
Recommended for
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Notice changes in appearance with aging
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Are experiencing menopausal symptoms like hot flashes, difficulty concentrating, etc
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Are suffering from PMS-related irritability or anxiety
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Have insomnia
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Feel physically weaker
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Are mentally fatigued or emotionally down
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Are gaining weight more easily than before
RESULTS
Coming Soon
FEATURES
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What is Bioidentical Hormone Replacement Therapy?
Bioidentical Hormone Replacement Therapy (BHRT) uses hormones that are chemically identical to those your body naturally produces. This approach helps restore hormonal balance while minimizing side effects. Hormones, released by endocrine glands such as the pituitary gland, thyroid, adrenal glands, ovaries, and testes, travel through the bloodstream to regulate numerous bodily functions. Their levels peak in your 20s and sharply decline in your 40s, contributing to aging symptoms. Poor lifestyle habits and chronic stress can further accelerate this decline. BHRT is suitable for people of all genders and ages, from women dealing with menopausal symptoms to men experiencing fatigue. For anyone seeking to maintain youthful beauty and vitality, BIANCA CLINIC provides personalized hormone prescriptions tailored to each patient’s symptoms and treatment goals.
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Personalized Treatment
At BIANCA CLINIC, the type and dosage of hormones administered through Bioidentical Hormone Replacement Therapy are precisely tailored to each patient’s individual test results. Based on detailed diagnostic data, the minimum effective dose is prescribed to supplement hormone deficiencies. In some cases, both progesterone and estrogen are supplemented; in others, only one may be prescribed depending on the patient’s needs. In addition to being used as a standalone treatment, hormone therapy can also be combined with other therapies depending on your symptoms and goals, such as surgical interventions or orthomolecular nutrition therapy. Dr. Maeda, drawing on her extensive experience, offers personalized "combination treatments" designed to maximize the synergistic benefits of hormone replacement.
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Downtime after Bioidentical Hormone Replacement Therapy
Excessive hormone supplementation may lead to hormone overdose symptoms. To prevent this, regular blood tests are conducted, and treatment proceeds in close consultation with your doctor.
※ The possibility and type of overdose symptoms may vary depending on the medication and individual constitution.
Types of Hormone Preparations Administered
At BIANCA CLINIC, hormone prescriptions are tailored to each patient’s symptoms and treatment goals. Below are the types of hormones we offer
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DHEA (Dehydroepiandrosterone)
Produced in the adrenal glands, DHEA is a precursor to testosterone (male hormone) and estrogen (female hormone), often called the “mother hormone”.
【Expected Benefits】
・Increased energy levels
・Reduced visible signs of aging
・Improved muscle strength
・Enhanced bone density
・Strengthened immune function
・Maintained mental well-being
【Side Effects】
・Oily skin
・Changes in hair growth
・Increased feelings of anger or anxiety
・High blood pressure
【Contraindications (Not suitable for)】
・Individuals with a history of hormone-sensitive tumors
・Those with severe liver dysfunction
・Pregnant or breastfeeding women
【Drug Interactions (Avoid with)】
・Certain antipsychotic medications
・Specific antiepileptic drugs -
Estrogen (Follicular Hormone)
Secreted by the ovaries, estrogen supports breast, uterus, and vaginal development, stimulates collagen production, and contributes to the health of the vascular, skeletal, joint, and brain systems. Levels fluctuate with the menstrual cycle and decline during menopause, triggering various symptoms.
【Expected Benefits】
・Alleviation of menopausal symptoms
・Prevention of bone density loss
・Cardiovascular health support
・Improved skin and hair condition
【Side Effects】
・Headaches
・Gastrointestinal issues
・Irregular genital bleeding
・Weight changes
・Breast tenderness or pain
・Changes in menstrual cycle
【Contraindications (Not suitable for)】
・Individuals with a history of hormone-sensitive tumors
・Those with unexplained vaginal bleeding
・Severe liver dysfunction
・History of thrombosis
【Drug Interactions (Avoid with)】
・Anticoagulants
・Tranexamic acid
・Certain antiepileptic drugs
・Specific antibiotics -
Testosterone (For Women)
While known as a male hormone, testosterone is essential for women too. It influences energy, muscle mass, bone density, and libido.
【Expected Benefits】
・Increased overall energy
・Muscle growth
・Fat reduction
・Enhanced bone density
・Increased libido
・Improved mental clarity and mood
【Side Effects】
・Skin issues (itching or rash)
・Sleep disturbances (e.g., sleep apnea)
・Weight gain (due to increased muscle and fluid retention)
・Emotional instability or heightened aggression
・High blood pressure or cardiovascular issues
【Contraindications (Not suitable for)】
・History of hormone-sensitive tumors
・Severe cardiovascular disease
・Severe liver dysfunction
・Pregnant women or those who may be pregnant
【Drug Interactions (Avoid with)】
・Certain cardiovascular medications
・Steroidal anti-inflammatory drugs
・Anticoagulants -
Testosterone (For Men)
A key hormone in male health, testosterone decline can lead to physical (e.g., muscle loss), psychological (e.g., depression), and sexual (e.g., reduced libido) symptoms.
【Expected Benefits】
・Improved overall energy
・Muscle growth
・Fat reduction
・Enhanced bone density
・Increased libido
・Improved mental clarity and mood
【Side Effects】
・Improved overall energy
・Muscle growth
・Fat reduction
・Enhanced bone density
・Increased libido
・Improved mental clarity and mood
【Contraindications (Not suitable for)】
・History of hormone-sensitive tumors
・Severe cardiovascular disease
・Severe liver dysfunction
【Drug Interactions (Avoid with)】
・Certain anticoagulants
・Tranexamic acid
・Some antiepileptic drugs
・Some antibiotics -
Progesterone (Luteal Hormone)
A female hormone that supports body temperature elevation, uterine lining stability, and breast tissue development in preparation for or during pregnancy. It also helps regulate appetite and maintain hormonal balance.
【Expected Benefits】
・Reduced menopausal symptoms
・Relief from PMS
・Improved sleep quality
・Normalized menstrual cycles
・Emotional stability
・Maintained bone density
【Side Effects】
・Headaches or dizziness
・Mood swings
・Breast tenderness or pain
・Weight gain
・Fatigue
【Contraindications (Not suitable for)】
・History of deep vein thrombosis or pulmonary embolism
・History of hormone-sensitive tumors
・Severe liver dysfunction
・Pregnancy (use during pregnancy is not recommended in some cases)
【Drug Interactions (Avoid with)】
・History of deep vein thrombosis or pulmonary embolism
・History of hormone-sensitive tumors
・Severe liver dysfunction
・Pregnancy (use during pregnancy is not recommended in some cases) -
Melatonin
Secreted by the pineal gland, melatonin regulates sleep and the body’s internal clock. It may also promote cellular renewal, reduce fatigue, and help with insomnia, jet lag, and Seasonal Affective Disorder (SAD)*.
*Seasonal Affective Disorder (SAD): Depression-like symptoms such as low mood, fatigue, and excessive sleeping that recur during specific seasons (usually fall to early spring).
【Expected Benefits】
・Better sleep quality
・Reduced time to fall asleep
・Fewer nighttime awakenings
・Mood improvement via circadian rhythm regulation
・Cellular protection
【Side Effects】
・Morning drowsiness
・Vivid dreams
・Headaches
・Temporary mood dips
・Mild nausea
※Take melatonin capsules before bed. A proper sleep environment—dark room, quality bedding—is also essential.
【Contraindications (Not suitable for)】
・Pregnant or breastfeeding women
・Individuals with severe autoimmune disorders
・Severe liver dysfunction
【Drug Interactions (Avoid with)】
・Certain antidepressants
・Sedatives
・Certain sleeping pills -
Thyroid Hormones (T3/T4)
These hormones, produced by the thyroid gland, regulate energy metabolism, including glucose and protein processing. While severe deficiency requires insurance-covered treatment, even mild deficiency can impair quality of life. At BIANCA CLINIC, private treatment using synthetic or natural thyroid hormones in low, carefully controlled doses is offered.
【Expected Benefits】
・Improved energy
・Better body temperature regulation
・Support for weight management
・Stabilized cardiac function
・Enhanced mood and overall well-being
【Side Effects】
・Increased heart rate
・Insomnia
・Weight fluctuations
・Tremors
・Indigestion
※Note: These can usually be managed with dose adjustments.
【Contraindications (Not suitable for)】
・Untreated adrenal insufficiency
・History of acute myocardial infarction
・Hyperthyroidism (excess thyroid hormone)
【Drug Interactions (Avoid with)】
・Certain antidepressants
・Insulin and other hypoglycemic agents
・Blood thinners like warfarin
TREATMENT PROCESS
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Initial Consultation
Discuss your concerns and symptoms openly, ask any questions you have about the treatment.
Discuss your concerns and symptoms openly, ask any questions you have about the treatment.
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Blood Test
A blood test will be conducted to measure key indicators, primarily hormone levels. You may also opt for the Epigenetic Clock Test and blood testing for Orthomolecular Nutrition Therapy simultaneously.
A blood test will be conducted to measure key indicators, primarily hormone levels. You may also opt for the Epigenetic Clock Test and blood testing for Orthomolecular Nutrition Therapy simultaneously.
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Start Treatment
Once you agree to Dr. Maeda’s treatment plan, therapy will begin. Before starting, confirmation will be made that you do not have any hormone-sensitive tumors, such as breast cancer or prostate cancer. Based on your test results, appropriate hormone formulations will be prescribed. Contact the clinic immediately if you experience any changes or unusual symptoms after starting treatment.
Once you agree to Dr. Maeda’s treatment plan, therapy will begin. Before starting, confirmation will be made that you do not have any hormone-sensitive tumors, such as breast cancer or prostate cancer. Based on your test results, appropriate hormone formulations will be prescribed. Contact the clinic immediately if you experience any changes or unusual symptoms after starting treatment.
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Follow-up
Regular medical checkups and blood tests are essential. The time to feel effects may vary, and your progress will be monitored through consistent evaluations for safe and effective treatment.
Regular medical checkups and blood tests are essential. The time to feel effects may vary, and your progress will be monitored through consistent evaluations for safe and effective treatment.
PRICE LIST
View the price list for Bioidentical Hormone Replacement Therapy
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Hormone + Orthomolecular test
Hormone + Orthomolecular test ¥82,500（tax inc.） -
Hormone test only
Hormone test only ¥55,000（tax inc.） -
Monthly medication costs (per item)
Testosterone injection (men) ¥33,000（tax inc.） Biestrogen cream ¥22,000（tax inc.） Progesterone capsule ¥22,000（tax inc.） DHEA capsule ¥11,000（tax inc.） Testosterone cream ¥22,000（tax inc.） Thyroid hormone capsule ¥16,500（tax inc.） Melatonin capsule ¥11,000（tax inc.）
FAQ
- Q When is the best time to start Bioidentical Hormone Replacement Therapy (BHRT)?
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A
It is recommended to start BHRT when hormone levels begin to decline. General guidelines are:
・Women: From their 40s to around 55 years old (about 5 years before and after menopause)
・Men: In their 40s to 50s.
The ideal time is after age 40, though those in their 20s or 30s experiencing symptoms such as PMS or PCOS may also benefit. Starting early may help prevent further hormone-related symptoms. - Q Are there any cases where BHRT cannot be administered?
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A
Treatment may be declined based on blood test results or medical history due to factors like overall health or smoking habits. Individuals with suspected or active hormone-sensitive tumors (e.g., breast or ovarian cancer) may not be eligible, as hormone therapy could accelerate the condition. Consult with your doctor and review contraindications for each hormone.
- Q How is BHRT administered?
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A
Administration varies by hormone type, generally through oral capsules or topical creams. The treatment is non-invasive and painless.
- Q When will I see results from BHRT, and how long should I continue?
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A
Most people see effects within 2 weeks to 3 months, though individual results vary. Some women report symptom relief by the end of menopause. If symptom management is the goal, treatment can stop then; others continue for long-term health maintenance. Please decide based on your personal objectives.
- Q What happens if I stop BHRT?
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A
If discontinued, hormone levels may gradually return to their pre-treatment state. Ongoing therapy is recommended for maintaining benefits.
- Q Are there any side effects from BHRT?
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A
Since BHRT uses hormones identical in structure to those produced in the body, it is designed to be gentle with relatively few side effects. Promptly contact the clinic if any unusual symptoms occur.
- Q Can BHRT help with female hair loss?
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A
Yes. Estrogen and progesterone—hormones closely linked to women’s hair health—are often supplemented as part of BHRT and may serve as a treatment option for FAGA (female pattern hair loss). Consult the clinic if you’ve noticed increased hair thinning with age.
- Q Are there any medications I should avoid when taking hormone formulations?
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A
While some medications (e.g., herbal or psychiatric treatments) can be taken safely, others may interfere with hormone therapy effectiveness or increase side effect risk. Inform your physician of all current medications before starting treatment.
- Q Is BHRT covered by health insurance?
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A
No. BHRT at BIANCA CLINIC is not covered by national health insurance and is provided as private, self-funded care. Contact the clinic for questions regarding treatment costs.